Andrea Lobo, PhD,  science writer—

Andrea Lobo holds a PhD in cell biology/neurosciences from the University of Coimbra-Portugal, where she studied stroke biology. As a research scientist for 19 years, Andrea participated in academic projects in multiple research fields, from stroke, gene regulation, cancer, and rare diseases. She has authored multiple research papers in peer-reviewed journals.

Articles by Andrea Lobo

Aspiration events tied to higher risk of respiratory complications

An aspiration event— when something other than air enters the lungs — increases the risk of lower respiratory tract infection and respiratory failure in people with Rett syndrome, a study found. Patients with known or suspected aspiration events more commonly had risk factors like epilepsy and difficulty swallowing, and…

Families say access to dental care can improve quality of life

Better access to dental care and resources can improve quality of life for girls with Rett syndrome, according to their parents. Parents interviewed for a study on oral health-related quality of life (OHRQOL) also said their own motivation and empowerment to address their daughters’ oral healthcare concerns affected overall…

Marvel’s MB204 improves social behaviors in Rett mice in study

Marvel Biosciences‘ MB204, an experimental treatment for Rett syndrome, was shown to improve social behaviors — with “durable” effects — in a mouse model of the disease. Based on these results, Marvel intends to seek orphan and/or rare disease designation from the U.S. Food and Drug Administration (FDA)…

Female Rett syndrome mouse model mimics patient gene dysregulation

A female mouse model of Rett syndrome manifested gene activity changes that began before the symptoms started and that mimicked those found in people with the condition. Biological pathways affected across the disease’s progression also overlapped with other neurodegenerative and addiction disorders. “Since RTT [Rett] in humans almost…

Targeting CB1Rs restores brain energy production in Rett mice

Increased levels of CB1 cannabinoid protein receptors, known as CB1Rs, may be tied to dysfunction of the brain’s mitochondria — its cellular energy-producing compartments — and to cognitive deficits in Rett syndrome, according to a study in a mouse model. The study also reported that blocking CB1Rs in the…

Rett patients see disease progression despite therapy: Study

Women and girls with Rett syndrome experience disease progression and increasing disease burden even as they rely on supportive therapies, a study found. Close to half of all patients in the study needed a hospital or emergency room visit, the researchers said. Children and adolescents saw “increasing disease severity…

IRSF names 3 centers of excellence for Rett clinical care

The International Rett Syndrome Foundation (IRSF) designated three new clinics as centers of excellence, saying they provide best-in-class clinical care for people with Rett syndrome. The designation comes with funding support from the foundation and integration into IRSF’s Center of Excellence Network, which now has 21 clinics…