Margarida Maia, PhD,  science writer—

Margarida is a biochemist (University of Porto, Portugal) with a PhD in biomedical sciences (VIB and KULeuven, Belgium). Her main interest is science communication. She is also passionate about design and the dialogue between art and science.

Articles by Margarida Maia

Cannabis-based oil eases symptoms in Rett syndrome girls

NTI164, a cannabis-based oil being developed by Neurotech International, may help girls with Rett syndrome communicate more easily, enjoy better moods, and have a better quality of life with few side effects, a small study in Australia found. The study, “Full-Spectrum Medicinal Cannabis Plant Extract 0.08% THC (NTI164)…

Intranasal delivery of human NGF eases Rett symptoms in mice

Into-the-nose delivery of a solution containing clinical-grade human nerve growth factor (NGF) improved cognitive and motor function in a mouse model of Rett syndrome, including in male mice with more severe and rapidly advancing symptoms, a study has found. This could be “a non-invasive and effective route of administration…

Taysha gets green light for dose escalation in TSHA-102 trial

Taysha Gene Therapies has received the needed approval to move forward with dose escalation in its Phase 1/2 trial testing TSHA-102, its gene therapy candidate for Rett syndrome, in adolescents and adults, the company announced. That green light from the study’s independent data monitoring committee (IDMC) — a group…

Intrathecal TSHA-102 leads to improvements in Rett mice

An injection of Taysha Gene Therapies’ experimental gene therapy TSHA-102 into the spinal canal of young mice modeling Rett syndrome can improve weight, survival, breathing, and motor skills, a preclinical study suggests. The data support using the intrathecal route in ongoing Phase 1/2…