Marisa Wexler, MS,  senior science writer—

Lack of a functional MeCP2 protein leads to Rett syndrome by altering levels of brain proteins associated with energy metabolism and protein regulation, a study in a mouse model suggests. These altered protein levels might also predict Rett syndrome’s progression, the investigators said. The study, “Brain protein…

Preliminary clinical data from a Phase 2 trial testing Anavex-2-73 suggest the investigational therapy is effective and safe for the treatment of Rett syndrome. Detailed results will be presented at the 6th European Rett Syndrome Conference, to be held in Tampere, Finland, Sept. 27-28, according to a press…

Therapy that engages multiple senses in a playful context may help improve hand coordination in children with Rett syndrome, a preliminary study suggests, but more research is needed. The study, “Sensory Integration and Functional Reaching in Children With Rett Syndrome/Rett-Related Disorders,” was published in the journal…

A new study reports an increasing trend in the number of prenatal genetic tests to detect spontaneous mutations that can cause conditions such as Rett syndrome. The study, “Prenatal diagnosis for de novo mutations: Experience from a tertiary center over a 10‐year period,” was published in Molecular…