According to their parents, children with Rett syndrome have diminished quality of life (QoL) across all measured dimensions, a study found. In the study’s parent-reported assessments, the neurodevelopmental disorder was associated with reduced family functioning, and with physical, emotional, and psychological symptoms that impact the children’s…
Skin conductance — the electrical activity on the surface of the skin in response to stimuli, as measured using wrist-worn devices — is indicative of changes in emotions and behaviors that affect the autonomic nervous system of Rett syndrome patients, a pilot study reports. Together, these alternations are known as…
Early administration of a compound intended to enhance signals between brain cells lessened disease severity, and improved overall health and survival in a mouse model of Rett syndrome. The improvements, which also included benefits in nerve cell activity, indicate that treatments enhancing neuronal activity early…
Girls and young women with Rett syndrome have a high level of both participation and engagement in social and restful family activities — but are not engaged in morning and evening daily routines — a study finds. While participation in such daily routines…
A $200,000 Comcast NBCUniversal grant has been awarded to The Arc to increase access to educational resources for students of color and economically disadvantaged youngsters with intellectual and developmental disabilities (IDD), which can include Rett syndrome.
The United States Patent and Trademark Office (USPTO) has issued an allowance for a patent submitted by DiamiR for methods the company developed that use microRNA (miRNA) as biomarkers of Rett syndrome and other neurodevelopmental diseases. Notices of Allowance are issued by…
Dystonia, or excessive involuntary muscle contractions, are linked in Rett syndrome with abnormal iron accumulation in certain brain regions, a study suggests. The study, “Correlation of dystonia severity and iron accumulation in Rett syndrome,” was published in the…
In people with Rett syndrome, cells known as fibroblasts have a distinct protein production profile — called a proteome — that overrepresents biological pathways related to immune function and inflammation, a small study reports. These findings may help researchers better…
Anavex 2-73 (blarcamesine), an investigational treatment for Rett syndrome, lessened the disease’s characteristic behavioral features, its severity, and levels of the glutamate biomarker with no serious side effects, top-line results of a Phase 2 clinical trial in adult patients show. Based on these findings, Anavex Life…
Viewers from around the world are invited to join in the virtual Reverse Rett Big Night In, a U.K. fundraiser benefitting Rett syndrome research, to be held Saturday, Dec. 5 at 3 p.m. EST (8 p.m. GMT). The live stream…
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